New Publication – Response reliability observed with voltage-sensitive dye imaging of cortical layer 2/3: the probability of activation hypothesis

POA model

A pervasive underlying assumption about sensory processing is that neural activity represents the world in a graded manner: the stronger the input, the stronger the response; the weaker the input, the weaker the response. In work from Dr. Clare Gollnick and colleagues, this assumption was directly considered and investigated through voltage sensitive dye imaging of activity across somatosensory cortex in the representation of tactile inputs.  Experimental evidence and theoretical analyses suggest that an alternative strategy may be at work, in which populations of neurons encode information in a more binary, probabilistic manner, and that the information is represented in a more distributed manner across the larger population. Read the full article for more…  Gollnick2016b

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